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Research shows that Vitamin B12 can harm the optic nerve in LHON patients

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The limited information from studies already conducted shows it could evoke mild fatigue

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"Health Canada won't approve it as a drug, but it slips through as a compounded natural health product, where the federal safety check basically doesn't happen." Health Canada considers NHP compounding within a practitioner-patient relationship distinct from manufacturing and not subject to the same regulatory oversight

The classification criteria then include a history of chronic widespread pain and the presence of 11 or more out of 18 tender points (TPs)