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The protective effects of KB could result from possible antioxidative activity, improved ATP synthesis, and from the effect on the ATP-sensitive potassium channel (KATP) (158, 159)

Overexpression of IGF-I receptor in OVCAR-3 cells had no protective effect, however ectopic expression of a constitutively active AKT2 did offer protection from the cytotoxic effects of ascorbyl stearate

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This unique property sets it apart from most therapeutic peptides and expands potential administration routes

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