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Novo Nordisk is planning a higher-dose version (CagriSema 2.4/7.2 mg, pairing standard cagrilintide with Wegovy HD-level semaglutide) in a new Phase 3 trial starting H2 2026

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Common Dose: Similar to CJC-1295 with DAC, 1-2 mg per week

Retatrutide-specific body-weight data has not been published, but semaglutide and tirzepatide studies measured 20% to 50% higher exposure in people weighing 120 to 155 lb than in a 185 lb reference

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To directly feed the heme-biosynthesis pathway, measure mitochondrial respiration, and trace metabolic flux in cellular and animal models