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Balercia G, Regoli F, Armeni T

Copper homeostasis and cuproptosis in health and disease

Recently this year, the Health Science Authority (HSA) of Singapore flagged five skincare creams for containing mercury, with one of the creams exceeding permissable limits by more than 40 000 times 7

This condition is experienced by 15% of those with male-factor infertility and 1% of the general male population

doi:10.1021/jm0509997 38

In vitro characterization is classically done on cloned human receptors expressed in cell lines (HEK293, CHO) via cAMP measurements (ELISA, FRET) or beta-arrestin recruitment (BRET, NanoBiT)