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In 2010, Americans Rana Tyson and her husband Chad were falsely accused of harming their 4-week-old twin daughters, who had unexplained fractures in their legs
Based on the 3/S ( and S are the standard deviation of 10 parallel blank measurements and the slope of the linear fitting equation, respectively), the LOD was 0.018 g/mL
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However, because of the concomitant hyperinsulinemia, the liver becomes inadequately hypersensitive to GH, which further worsens the situation