[31] Mitochondrial Biogenesis : Butyrate promotes the formation of new mitochondria, your cells' power plants
Patient samples (serum/plasma) contain various components that may interfere with the measurement (matrix effects)
Understanding this nuanced risk-benefit profile enables informed shared decision-making between healthcare providers and patients considering GLP-1 therapy
Over-the-counter antidiarrheal medications such as loperamide (Imodium) may provide short-term symptomatic relief for mild to moderate diarrhea
Providers will also assess mental health concerns, as some patients may experience depression or suicidal thoughts
FIGURE 5 4 Discussion Current research on the pathogenesis of T2D increasingly focuses on the gut-islet axis, where gut microbiota-derived SCFAs (Ng et al., 2022), particularly through promoting GLP-1 secretion, represent a significant therapeutic target (Zhuang et al., 2021