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Interestingly, the hypothalamus is also responsible for regulating temperature changes that cause hot flashes

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*Correspondence: Marco Centanni, [email protected] This article was submitted to Thyroid Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In particular, animal models have shown that GLP-1 RAs can reduce necrosis in random-pattern skin flaps [97]