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Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes

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In another study, GLP-1 protected against methylglyoxal-induced pheochromocytoma (PC12) cell apoptosis though the PI3K/Akt/mTOR/GCLc/redox signaling pathway (193)

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FIGURE 3 To functionally link the altered SCFAs to GLP-1 secretion, we employed GLUTag cells under high-glucose (HG) conditions to mimic diabetic enteroendocrine dysfunction