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For instance, according to the latest International Diabetes Federation (IDF) Diabetes Atlas (2025), approximately 11.1% of adults aged 2079 yearsabout 1 in 9 peopleare living with diabetes globally, and more than 4 in 10 of those individuals remain undiagnosed

But heres whats often missed: GLP itself is not new

475 By the way, a clinical study published in Nature Metabolism detailed the effects of semaglutide and dapagliflozin (an SGLT2 inhibitor) on blood sugar control in patients with T2DM of different pathophysiological types

Annu Rev Physiol

Insulin dose adjustments with add-on glucagon-like peptide-1 receptor (GLP-1R) agonists in clinical practice

Table S1